BDBM745106 3-{2-[p-(3- morpholinopropoxy) phenylamino]-4- pyrimidinylamino}- 7-quinolinol::US20250171431, Compound 408

SMILES Oc1ccc2cc(Nc3ccnc(Nc4ccc(OCCCN5CCOCC5)cc4)n3)cnc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745106   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745106(3-{2-[p-(3- morpholinopropoxy) phenylamino]-4- pyr...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent