BDBM745110 2-[3-methoxy-4-(3- piperidinopropoxy) phenylamino]- 4-(2-methyl-3,4- dihydro-2H-1-thia-5- azanaphth-7- ylamino)pyrimidine::US20250171431, Compound 412

SMILES COc1cc(Nc2nccc(Nc3cnc4ccc(Cl)cc4c3)n2)ccc1OCCCN1CCOCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745110   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745110(2-[3-methoxy-4-(3- piperidinopropoxy) phenylamino]...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent