BDBM745114 4-(8-chloro-3- quinolylamino)-2-[p-(3- morpholinopropoxy) phenylamino]pyrimidine::US20250171431, Compound 416

SMILES Clc1cccc2cc(Nc3ccnc(Nc4ccc(OCCCN5CCOCC5)cc4)n3)cnc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745114   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745114(4-(8-chloro-3- quinolylamino)-2-[p-(3- morpholinop...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent