BDBM745116 2-{4-(3-piperidinopropoxy)- 3-[(tetrahydro-2H-pyran-4- yl)methoxyphenylamino}- 4-(3- quinolylamino)pyrimidine::US20250171431, Compound 418

SMILES c1cc(Nc2cnc3c(c2)CCCC3)nc(Nc2ccc(OCCCN3CCCCC3)c(OCC3CCOCC3)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745116   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745116(2-{4-(3-piperidinopropoxy)- 3-[(tetrahydro-2H-pyra...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent