BDBM745148 2-hydroxy-1-(4-{p-[4-(3- quinolylamino)-2- pyrimidinylamino]phenyl}- 1-piperazinyl)-1-propanone::US20250171431, Compound 465

SMILES CC(O)C(=O)N1CCN(c2ccc(Nc3nccc(Nc4cnc5ccccc5c4)n3)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745148   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745148(2-hydroxy-1-(4-{p-[4-(3- quinolylamino)-2- pyrimid...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent