BDBM745152 4-(6,7-difluoro-3-quinolylamino)- 2-(5-methoxy-6-morpholino-3- pyridylamino)pyrimidine::US20250171431, Compound 469

SMILES COc1cc(Nc2nccc(Nc3cnc4cc(F)c(F)cc4c3)n2)cnc1N1CCOCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745152   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745152(4-(6,7-difluoro-3-quinolylamino)- 2-(5-methoxy-6-m...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent