BDBM745159 1-{5-[4-(6-chloro-3- quinolylamino)-2- pyrimidinylamino]-3-methoxy-2-pyridyl}-4-methyl-4-piperidinol::US20250171431, Compound 476

SMILES COc1cc(Nc2nccc(Nc3cnc4ccc(Cl)cc4c3)n2)cnc1N1CCC(C)(O)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745159   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745159(1-{5-[4-(6-chloro-3- quinolylamino)-2- pyrimidinyl...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent