BDBM745163 4-(6-chloro-3-quinolylamino)-2- [6-(3,3-dimethyl-4- methyl-1-piperazinyl)-5- methoxy-3- pyridylamino] pyrimidine::US20250171431, Compound 480

SMILES COc1cc(Nc2nccc(Nc3cnc4ccc(Cl)cc4c3)n2)cnc1N1CCN(C)C(C)(C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745163   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745163(4-(6-chloro-3-quinolylamino)-2- [6-(3,3-dimethyl-4...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent