BDBM745164 4-(6-chloro-3-quinolylamino)-2- {5-methoxy-6- [4-(3-oxetanyl)- 1-piperazinyl]-3- pyridylamino}pyrimidine::US20250171431, Compound 481

SMILES COc1cc(Nc2nccc(Nc3cnc4ccc(Cl)cc4c3)n2)cnc1N1CCN(C2COC2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745164   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745164(4-(6-chloro-3-quinolylamino)-2- {5-methoxy-6- [4-(...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent