BDBM745187 2-(2,3-dihydro-1,4-benzodioxin-6- ylamino)-4-(3- quinolylamino)pyrimidine::US20250171431, Compound 505

SMILES c1ccc2ncc(Nc3ccnc(Nc4ccc5c(c4)OCCO5)n3)cc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745187   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM745187(2-(2,3-dihydro-1,4-benzodioxin-6- ylamino)-4-(3- q...)
Affinity DataIC50: 500nMAssay Description:The media was removed and replaced by 50 μL of 1× lysis buffer from the AlphaLISA kit (with 1× of cOmplete™ protease inhibitor). The plates were seal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent