BDBM745192 3-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]quinazolin-2-yl)cyclopropyl]-N-methylbenzamide::US20250171447, Ex-4

SMILES CNC(=O)c1cccc(C2CC2c2nc3c4cccc(OC)c4nc(N)n3n2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745192   

TargetAdenosine receptor A2a(Human)TBA
LigandPNGBDBM745192(3-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]qui...)
Affinity DataIC50: 0.400nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)TBA
LigandPNGBDBM745192(3-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]qui...)
Affinity DataIC50: 25nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent