BDBM745197 7-methoxy-2-[2-(3- methyl[1,2,4]triazolo [4,3-a]pyridin-6-yl)cyclopropyl][1,2,4] triazolo[1,5-c] quinazolin-5-amine::US20250171447, Ex-9

SMILES COc1cccc2c1nc(N)n1nc(C3CC3c3ccc4nnc(C)n4c3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745197   

TargetAdenosine receptor A2a(Human)TBA
LigandPNGBDBM745197(7-methoxy-2-[2-(3- methyl[1,2,4]triazolo [4,3-a]py...)
Affinity DataIC50: 2nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)TBA
LigandPNGBDBM745197(7-methoxy-2-[2-(3- methyl[1,2,4]triazolo [4,3-a]py...)
Affinity DataIC50: 337nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent