BDBM745227 9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- methoxy[1,2,4]triazolo [1,5-c]quinazolin- 5-amine::US20250171447, Ex-39

SMILES COc1cc(F)cc2c1nc(N)n1nc(C3CC3(F)c3ccccc3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745227   

TargetAdenosine receptor A2a(Human)TBA
LigandPNGBDBM745227(9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- meth...)
Affinity DataIC50: 0.600nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)TBA
LigandPNGBDBM745227(9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- meth...)
Affinity DataIC50: 71.9nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent