BDBM745251 2-{6-[trans-3-(5- amino-7,9- difluoro[1,2,4]triazolo [1,5-c]quinazolin-2- yl)cyclobutyl]pyridin- 3-yl} propan-2-ol::US20250171447, Ex-64

SMILES CC(C)(O)c1ccc([C@H]2C[C@H](c3nc4c5cc(F)cc(F)c5nc(N)n4n3)C2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745251   

TargetAdenosine receptor A2b(Human)TBA
LigandPNGBDBM745251(2-{6-[trans-3-(5- amino-7,9- difluoro[1,2,4]triazo...)
Affinity DataIC50: 1.70nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)TBA
LigandPNGBDBM745251(2-{6-[trans-3-(5- amino-7,9- difluoro[1,2,4]triazo...)
Affinity DataIC50: 16nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent