BDBM745385 9-Nitropyrido[3'',4'':4,5]pyrimido[1,2-a]indole-5,11-dione ::US20250171452, Compound 57

SMILES CON=c3c1cc(C(=O)NCCNC(=O)OC(C)(C)C)ccc1n4c(=O)c2ccc(Cl)cc2nc34

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745385   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745385(9-Nitropyrido[3',4':4,5]pyrimido[1,2-a]indole-5,11...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent