BDBM745388 7,8-Difluoroindolo[2,1-b]quinazoline-6,12-dione ::US20250171452, Compound 60

SMILES N#Cc1ccc3c(c1)c(=NO)c4nc2cc(Cl)ccc2c(=O)n34

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745388   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745388(7,8-Difluoroindolo[2,1-b]quinazoline-6,12-dione |...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent