BDBM745419 Synthesis of (Z)—N-((8-fluoro-6-(methoxyimino)-12-oxo-6,12-dihydroindolo[2,1-b]quinazolin-3-yl)methyl)methanesulfonamide ::US20250171452, Compound 91

SMILES CON=c3c1cc(F)ccc1n4c(=O)c2ccc(CNS(C)(=O)=O)cc2nc34

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745419   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745419(Synthesis of (Z)—N-((8-fluoro-6-(methoxyimino)-12-...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent