BDBM745423 Synthesis of N-((8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-3-yl)methyl)methanesulfonamide ::US20250171452, Compound 95

SMILES CS(=O)(=O)NCc1ccc2c(=O)n3c(nc2c1)C(=O)c1cc(F)ccc1-3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745423   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745423(Synthesis of N-((8-fluoro-6,12-dioxo-6,12-dihydroi...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent