BDBM745499 US20250171454, Compound I-82

SMILES COc1c(F)cc(-c2cc(Cn3cnc4c(NCCCCCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)ncnc43)c(N3CCC[C@](N)(c4ccccn4)C3)cn2)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745499   

TargetHistone-lysine N-methyltransferase NSD2 [2-1365](Human)
K36 Therapeutics

US Patent
LigandPNGBDBM745499(US20250171454, Compound I-82)
Affinity DataIC50: 1.00E+3nMAssay Description:A reaction mixture was prepared by adding oligonucleosomes from chicken (0.05 mg/mL) to freshly prepared reaction buffer containing 50 mM Tris-HCl (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent