BDBM745510 5,8-diazaspiro[2.6]nonan-8-yl-[1- (4-methoxyphenyl)-1,4,6,7- tetrahydropyrano[4,3-c]pyrazol-3- yl]methanone::US20250171467, Compound 8

SMILES COc1ccc(-n2nc(C(=O)N3CCNCC4(CC4)C3)c3c2CCOC3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745510   

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745510(5,8-diazaspiro[2.6]nonan-8-yl-[1- (4-methoxyphenyl...)
Affinity DataEC50:  1.20E+3nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent