BDBM745515 Racemic-(6-fluoro-1,4-diazepan-1- yl)-[1-(4-methoxyphenyl)-1,4,6,7- tetrahydropyrano[4,3-c]pyrazol-3- yl]methanone::US20250171467, Compound 13

SMILES COc1ccc(-n2nc(C(=O)N3CCNCC(F)C3)c3c2CCOC3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745515   

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745515(Racemic-(6-fluoro-1,4-diazepan-1- yl)-[1-(4-methox...)
Affinity DataEC50:  2.50E+3nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent