BDBM745516 [1-[4-methoxy-3- (trifluoromethyl)phenyl]-1,4,6,7- tetrahydropyrano[4,3-c]pyrazol-3- yl]-(4-methyl-1,4-diazepan-1- yl)methanone::US20250171467, Compound 14

SMILES COc1ccc(-n2nc(C(=O)N3CCCN(C)CC3)c3c2CCOC3)cc1C(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745516   

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745516([1-[4-methoxy-3- (trifluoromethyl)phenyl]-1,4,6,7-...)
Affinity DataEC50:  320nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent