BDBM746124 (4aR,8aR)-6-[5-chloro-1-(1- cyclopropyl-1H-pyrazol-4- yl)-1H-indazol-6- yl]octahydro-1H- pyrido[3,4-b][1,4]oxazine::US12319671, Example 6.52

SMILES Clc1cc2cnn(-c3cnn(C4CC4)c3)c2cc1N1CC[C@H]2NCCO[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746124   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746124((4aR,8aR)-6-[5-chloro-1-(1- cyclopropyl-1H-pyrazol...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent