BDBM746132 (S or R)-1-(1-(1-(bicyclo[1.1.1]pentan-1-yl)-1H-pyrazol-4-yl)-5-chloro-1H-indazol-6-yl)-4-(tetrahydrofuran-3-yl)piperidin-4-ol (Ex. 6.60) and (R or S)-1-(1-(1-(bicyclo[1.1.1]pentan-1-yl)-1H-pyrazol-4-yl)-5-chloro-1H-indazol-6-yl)-4-(tetrahydrofuran-3-yl)piperidin-4-ol (Ex. 6.61)::US12319671, Example 6.60

SMILES OC1(C2CCOC2)CCN(c2cc3c(cnn3-c3cnn(C45CC(C4)C5)c3)cc2Cl)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746132   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746132((S or R)-1-(1-(1-(bicyclo[1.1.1]pentan-1-yl)-1H-py...)
Affinity DataIC50: 442nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent