BDBM746157 [3-(4-{5-chloro-6-[4- (3-methyloxetan-3- yl)piperazin-1-yl]- 1H-indazol-1-yl}-1H- pyrazol-1- yl)bicyclo[1.1.1]pentan- 1-yl]methanol::US12319671, Example 7.2

SMILES CC1(N2CCN(c3cc4c(cnn4-c4cnn(C56CC(CO)(C5)C6)c4)cc3Cl)CC2)COC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746157   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746157([3-(4-{5-chloro-6-[4- (3-methyloxetan-3- yl)pipera...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent