BDBM746218 1-[1-(bicyclo[1.1.1]pentan- 1-yl)-1H-pyrazol-4-yl]-5- chloro-6-[4-(3- methyloxetan-3- yl)piperazin-1-yl]-1H- pyrazolo[3,4-b]pyridine::US12319671, Example 20.6

SMILES CC1(N2CCN(c3nc4c(cnn4-c4cnn(C56CC(C5)C6)c4)cc3Cl)CC2)COC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746218   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746218(1-[1-(bicyclo[1.1.1]pentan- 1-yl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent