BDBM746366 ethyl 4-(3-(((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)methyl)isoxazol-5-yl)piperidine-1-carboxylate::US12319672, Example 1.151

SMILES CCOC(=O)N1CCC(c2cc(C[C@H]3O[C@H](CO)[C@H](O)[C@H](n4cc(-c5ccc(C)c(F)c5F)nn4)[C@H]3OC)no2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746366   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746366(ethyl 4-(3-(((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4...)
Affinity DataIC50: 19nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746366(ethyl 4-(3-(((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4...)
Affinity DataIC50: 1.02E+3nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent