BDBM746549 (2R,3R,4R,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-2-(hydroxymethyl)-6-((3-(3-methyloxetan-3-yl)isoxazol-5-yl)methyl)tetrahydro-2H-pyran-3,5-diol::US12319672, Example 1.335

SMILES Cc1ccc(-c2cn([C@H]3[C@@H](O)[C@@H](CO)O[C@H](Cc4cc(C5(C)COC5)no4)[C@@H]3O)nn2)c(F)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746549   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746549((2R,3R,4R,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl...)
Affinity DataIC50: 26nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746549((2R,3R,4R,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl...)
Affinity DataIC50: 3.78E+3nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent