BDBM746594 2-(((2R,3R,4S,5R,6R)-2-((5-(tert-butyl)isoxazol-3-yl)methyl)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)acetic acid::US12319672, Example 2.27

SMILES Cc1ccc(-c2cn([C@H]3[C@@H](O)[C@@H](CO)O[C@H](Cc4cc(C(C)(C)C)on4)[C@@H]3OCC(=O)O)nn2)c(F)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746594   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746594(2-(((2R,3R,4S,5R,6R)-2-((5-(tert-butyl)isoxazol-3-...)
Affinity DataIC50: 24nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746594(2-(((2R,3R,4S,5R,6R)-2-((5-(tert-butyl)isoxazol-3-...)
Affinity DataIC50: 5.28E+3nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent