BDBM748583 US20250188030, Compound J10

SMILES Cn1cc(-c2ccc(O[C@@H]3CC[C@@H](NC(=O)[C@]4(F)CNC5(CCC5)C4)C3)c(-c3cccc(F)c3C3CCC3)c2)c(C(=O)O)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 748583   

TargetHistone acetyltransferase KAT2A(Human)
Pfizer

US Patent
LigandPNGBDBM748583(US20250188030, Compound J10)
Affinity DataKi:  0.270nMAssay Description:KAT2A/B Assay Protocol:A) Compound preparation1) Prepare 10 mM stock solutions in 100% DMSO from solid material.2) Serial dilute 10 mM, 1 mM, 0.1 or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT2B(Human)
Pfizer

US Patent
LigandPNGBDBM748583(US20250188030, Compound J10)
Affinity DataKi:  0.490nMAssay Description:KAT2A/B Assay Protocol:A) Compound preparation1) Prepare 10 mM stock solutions in 100% DMSO from solid material.2) Serial dilute 10 mM, 1 mM, 0.1 or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent