BDBM748858 N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]-2-pyridyl]-2-(1,3,5-trimethylpyrazol-4-yl)acetamide::US20250188075, Example 17

SMILES Cc1nn(C)c(C)c1CC(=O)Nc1cc(-c2[nH]c3cccnc3c2-c2ccccn2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 748858   

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748858(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 2.97nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
The Broad Institute

US Patent
LigandPNGBDBM748858(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 6.87nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform gamma-3(Human)
The Broad Institute

US Patent
LigandPNGBDBM748858(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 68.2nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM748858(N-[4-[3-(2-pyridyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]...)
Affinity DataIC50: 124nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white low volume 384-well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent