BDBM749380 US20250188102, Compound SHEN211

SMILES [2H]C([2H])([2H])n1cnc(Cn2c(=O)[nH]/c(=N\c3cc4cn(C)nc4cc3Cl)n(Cc3cc(F)c(F)cc3F)c2=O)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 749380   

TargetReplicase polyprotein 1ab(2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 25nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-HKU1)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 38nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 45nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a [P3395H](2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 51nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 133nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab [E3429V](2019-nCoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 1.35E+3nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(MERS-CoV)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 4.67E+3nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-NL63)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 2.60E+4nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Jkt Biopharma Co.

US Patent
LigandPNGBDBM749380(US20250188102, Compound SHEN211)
Affinity DataIC50: 6.01E+6nMAssay Description:The fluorescence resonance energy transfer method reported in the literature is adopted (J in et al 0.2020. Structure of Mprofrom SARS-CoV-2 and disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent