BDBM750180 N-(4-(8-amino-3,6- dimethylimidazo[1,5- a]pyrazin-1-yl)-3- methylphenyl)-2-(3- fluorophenyl)-2- hydroxyacetamide::US12331054, Example 3

SMILES Cc1cn2c(C)nc(-c3ccc(NC(=O)C(O)c4cccc(F)c4)cc3C)c2c(N)n1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 750180   

TargetInterferon-induced, double-stranded RNA-activated protein kinase /Eukaryotic translation initiation factor 2-alpha kinase 3 [536-1116]/Small ubiquitin-related modifier 1/eIF-2-alpha kinase GCN2 (Human)
Hibercell

US Patent

LigandBDBM750180(N-(4-(8-amino-3,6- dimethylimidazo[1,5- a]pyrazin-...)Copy SMILES

Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/9/2025
Entry Details
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