BDBM750201 N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imidazo[1,5- a]pyrazin-1-yl]-3- methyl-phenyl]-2- (3-fluorophenyl)-2- hydroxy-acetamide::US12331054, Example 32

SMILES [2H]C([2H])([2H])c1nc(-c2ccc(NC(=O)C(O)c3cccc(F)c3)cc2C)c2c(N)ncc(Cl)n12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 750201   

LigandPNGBDBM750201(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent