BDBM750334 N-(4-(8-amino- 3,5-dimethyl- imidazo[1,5-a] pyrazin-1-yl)-2- fluoro-3-methyl- phenyl)-2-(3- fluorophenyl)- 2-hydroxy- acetamide::US12331054, Example 169

SMILES Cc1c(-c2nc(C)n3c(C)cnc(N)c23)ccc(NC(=O)C(O)c2cccc(F)c2)c1F

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 750334   

TargetInterferon-induced, double-stranded RNA-activated protein kinase /Eukaryotic translation initiation factor 2-alpha kinase 3 [536-1116]/Small ubiquitin-related modifier 1/eIF-2-alpha kinase GCN2 (Human)TBA

LigandBDBM750334(N-(4-(8-amino- 3,5-dimethyl- imidazo[1,5-a] pyrazi...)Copy SMILES

Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In Depth
Date in BDB:
TBA
Entry Details
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