BDBM751303 9-benzyl-8-(2- chloro-3-((1- methylpiperidin- 4-yl)oxy) phenyl)-6-(1- methylcyclo- propoxy)-9H- purine::US20250195530, Example D9

SMILES CN1CCC(Oc2cccc(-c3nc4c(OC5(C)CC5)ncnc4n3Cc3ccccc3)c2Cl)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751303   

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandPNGBDBM751303(9-benzyl-8-(2- chloro-3-((1- methylpiperidin- 4-yl...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent