BDBM753081 US12338220, Example 69::US20250353820, Example 69

SMILES Cn1nc(C(=O)NCc2ccc(C#N)cc2)c2c1C(=O)N(CC1(S(=O)(=O)C(C)(C)CNCCO)CC1)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 753081   

TargetDNA polymerase(HHV-5)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 753081BDBM753081(US12338220, Example 69 | US20250353820, Example 69)
Affinity DataIC50: 1nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent

TargetSerine/threonine protein kinase UL97(HHV-5)
Novartis AG; Gilead Sciences, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 753081BDBM753081(US12338220, Example 69 | US20250353820, Example 69)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent

TargetDNA polymerase catalytic subunit(HHV-1)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 753081BDBM753081(US12338220, Example 69 | US20250353820, Example 69)
Affinity DataIC50: 40nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent

TargetMajor DNA-binding protein(HHV-1)
Novartis AG; Gilead Sciences, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 753081BDBM753081(US12338220, Example 69 | US20250353820, Example 69)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent