BDBM754026 US20250206759, Example 82

SMILES Oc1cc(-c2ncc3c(N4CC5CCCC(C4)N5)nc(OCC4C5CCC(C5)N4CCCF)nc3c2F)c2c(F)c(F)ccc2c1

InChI Key InChIKey=QPAQJPHBCVNPOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754026   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754026(US20250206759, Example 82)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent