BDBM755209 US20250213705, Compound 103

SMILES CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N(CCCOc1cc(C#N)cc(C#N)c1)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755209   

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755209(US20250213705, Compound 103)
Affinity DataKi:  0.00300nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755209(US20250213705, Compound 103)
Affinity DataKd:  0.169nMAssay Description:The interaction of PSMA-binding variants with human FOLH1 was measured with Surface Plasmon Resonance (SPR) technology. Biotinylated FOLH1 was captur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755209(US20250213705, Compound 103)
Affinity DataIC50: 0.435nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent