BDBM755225 US20250213705, Compound 120

SMILES C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cccc(C(=O)O)c1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755225   

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755225(US20250213705, Compound 120)
Affinity DataKi:  0.00200nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755225(US20250213705, Compound 120)
Affinity DataKd:  0.141nMAssay Description:The interaction of PSMA-binding variants with human FOLH1 was measured with Surface Plasmon Resonance (SPR) technology. Biotinylated FOLH1 was captur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetGlutamate carboxypeptidase 2(Human)
Bright Peak Therapeutics

US Patent
LigandPNGBDBM755225(US20250213705, Compound 120)
Affinity DataIC50: 0.334nMAssay Description:Prepare a working solution of 100 μM Amplex® Red reagent containing 0.25 U/mL HRP, 0.08 U/mL L-glutamate oxidase, 0.5 U/mL 1-glutamate-pyruvate trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent