BDBM757542 N-[(5-(tert-butyl)-2-(2,2,2-trifluoroethoxy)phenyl)sulfonyl]-6-(dimethylamino)benzofuran-2-carboxamide::US12357603, Example 181

SMILES CN(C)c1ccc2cc(C(=O)NS(=O)(=O)c3cc(C(C)(C)C)ccc3OCC(F)(F)F)oc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757542   

LigandPNGBDBM757542(N-[(5-(tert-butyl)-2-(2,2,2-trifluoroethoxy)phenyl...)
Affinity DataIC50: 11.8nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))TBA
LigandPNGBDBM757542(N-[(5-(tert-butyl)-2-(2,2,2-trifluoroethoxy)phenyl...)
Affinity DataIC50: 43.5nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent