BDBM757546 N-((5-(tert-butyl)-2-methoxyphenyl)sulfonyl)-6-(dimethylamino)benzofuran-2-carboxamide::US12357603, Example 185

SMILES COc1ccc(C(C)(C)C)cc1S(=O)(=O)NC(=O)c1cc2ccc(N(C)C)cc2o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757546   

LigandPNGBDBM757546(N-((5-(tert-butyl)-2-methoxyphenyl)sulfonyl)-6-(di...)
Affinity DataIC50: 2.63nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM757546(N-((5-(tert-butyl)-2-methoxyphenyl)sulfonyl)-6-(di...)
Affinity DataIC50: 13.9nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent