BDBM757556 6-(Dimethylamino)-N-((2-ethoxyphenyl)sulfonyl)-4-(trifluoromethyl)benzofuran-2-carboxamide::US12357603, Example 195

SMILES CCOc1ccccc1S(=O)(=O)NC(=O)c1cc2c(C(F)(F)F)cc(N(C)C)cc2o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757556   

LigandPNGBDBM757556(6-(Dimethylamino)-N-((2-ethoxyphenyl)sulfonyl)-4-(...)
Affinity DataIC50: 5.73nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM757556(6-(Dimethylamino)-N-((2-ethoxyphenyl)sulfonyl)-4-(...)
Affinity DataIC50: 14.7nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent