BDBM757609 (5R)-5-ethyl-3-(5- spiro[2H- benzofuran-3,1''- cyclopropane]-4- yloxypyrazin-2- yl) imidazolidine- 2,4-dione::US12358901, Example 10

SMILES CC[C@H]1NC(=O)N(c2cnc(Oc3cccc4c3C3(CC3)CO4)cn2)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757609   

TargetPotassium voltage-gated channel subfamily C member 1(Human)
Autifony Therapeutics

US Patent
LigandPNGBDBM757609((5R)-5-ethyl-3-(5- spiro[2H- benzofuran-3,1'- cycl...)
Affinity DataEC50:  2.34E+3nMAssay Description:Experiments are conducted at r.t. using IonWorks Quattro™ planar array electrophysiology technology (Molecular Devices Corp.) with PatchPlate™ PPC. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily C member 1(Human)
Autifony Therapeutics

US Patent
LigandPNGBDBM757609((5R)-5-ethyl-3-(5- spiro[2H- benzofuran-3,1'- cycl...)
Affinity DataEC50:  3.55E+3nMAssay Description:Experiments are conducted at r.t. using IonWorks Quattro™ planar array electrophysiology technology (Molecular Devices Corp.) with PatchPlate™ PPC. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent