BDBM757805 N-[3-[7-[4-fluoro-2-(2-methoxyethoxy)phenyl]-4-(1,2,3,4-tetrahydroisoquinolin-6-yl)thieno[3,2-c]pyridin-6-yl]phenyl]prop-2-enamide ::US20250230138, Compound 12

SMILES C=CC(=O)Nc1cccc(-c2nc(-c3ccc4c(c3)CCNC4)c3ccsc3c2-c2ccc(F)cc2OCCOC)c1

InChI Key InChIKey=CEIJAZXDCYMWAZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757805   

TargetGTPase KRAS/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
TheRas

US Patent

LigandBDBM757805(N-[3-[7-[4-fluoro-2-(2-methoxyethoxy)phenyl]-4-(1,...)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:SPR binding experiments were collected on a Biacore 8K Instrument (Cytiva). Neutravidin (Pierce) was amine coupled to the carboxymethylated dextran s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/30/2025
Entry Details
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