BDBM75852 2-(7-azabicyclo[2.2.1]heptan-7-yl)-N-(8-methoxy-4-methyl-2-oxo-1H-quinolin-6-yl)-5,7-dihydrofuro[3,4-b]pyridine-3-carboxamide::US20250382308, Example 39

SMILES COc1cc(NC(=O)c2cc3c(nc2N2C4CCC2CC4)COC3)cc2c(C)cc(=O)[nH]c12

InChI Key InChIKey=MFWWKWDPVGXYAL-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75852   

TargetBromodomain-containing protein 4 [58-164](Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75852BDBM75852(2-(7-azabicyclo[2.2.1]heptan-7-yl)-N-(8-methoxy-4-...)
Affinity DataKd:  7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75852BDBM75852(2-(7-azabicyclo[2.2.1]heptan-7-yl)-N-(8-methoxy-4-...)
Affinity DataKd:  300nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75852BDBM75852(2-(7-azabicyclo[2.2.1]heptan-7-yl)-N-(8-methoxy-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent