BDBM75856 US20250382308, Example 43

SMILES COC1C=C(NC(=O)C2C=C3COCC3=NC2N2C[C@H](F)[C@@H](F)C2)C=C2C(C)=CC(=O)NC21

InChI Key InChIKey=HSKOBVPWCCDGEI-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75856   

TargetBromodomain-containing protein 4 [58-164](Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75856BDBM75856(US20250382308, Example 43)
Affinity DataKd:  18nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75856BDBM75856(US20250382308, Example 43)
Affinity DataKd:  400nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 75856BDBM75856(US20250382308, Example 43)
Affinity DataIC50: 1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent