BDBM762902 US20250250263, Compound 34::US20260102395, Compound 34

SMILES FC(F)c1nnc(-c2ccc(COc3ccc4cccnc4c3)nc2)o1

InChI Key InChIKey=SIRQDBNCXOYBKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 762902   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762902BDBM762902(US20250250263, Compound 34 | US20260102395, Compou...)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762902BDBM762902(US20250250263, Compound 34 | US20260102395, Compou...)
Affinity DataIC50: 50nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, if app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762902BDBM762902(US20250250263, Compound 34 | US20260102395, Compou...)
Affinity DataIC50: 1.00E+5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762902BDBM762902(US20250250263, Compound 34 | US20260102395, Compou...)
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, if app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent