BDBM762927 4-((1S,3S,5R)-8-((5-Cyclopropyl-7-methyl-1H-indol-4-yl)methyl)-3-ethoxy-8-azabicycl o[3.2.1]octan-1-yl)benzoic acid 4::US20250250267, Example 4

SMILES CCO[C@H]1C[C@H]2CC[C@](c3ccc(C(=O)O)cc3)(C1)N2Cc1c(C2CC2)cc(C)c2[nH]ccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 762927   

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762927(4-((1S,3S,5R)-8-((5-Cyclopropyl-7-methyl-1H-indol-...)
Affinity DataIC50: 1.60nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent