BDBM762937 US20250250263, Compound 179::US20260102395, Compound 179

SMILES Fc1cc(-c2nnc(C(F)F)o2)cnc1COc1cccc2ncncc12

InChI Key InChIKey=ACCMEKSDOUIBQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 762937   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762937BDBM762937(US20250250263, Compound 179 | US20260102395, Compo...)
Affinity DataIC50: 50nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, if app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 762937BDBM762937(US20250250263, Compound 179 | US20260102395, Compo...)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent